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KMID : 0370220040480030213
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Yakhak Hoeji
2004 Volume.48 No. 3 p.213 ~ p.217
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Activity of Glutathione S-transferase and Effect of Alcohol Decomposition on the Fruit of Hovenia dulcis Thunb
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차배천/Cha BC
이은희/이은/박행호/Lee EH/Lee E/Park HH
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Abstract
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For the determination of glutathione S-transferase activity, a new method was established by using HPLC system. Moreover, amount of enzyme for a optimum reaction was determine d by a comparative study with a variety concentration of enzyme. Using a established method, activity of glutathione S-transferase that is alcohol metabolizing enzyme was investigated on the fruit of Hovenia dulcis Thunb. As the result of experiment, EtOH and H2O extracts of the fruit of Hovenia dulcis Thunb showed visible a synergistic effect of glutathione S-transferase activiy on a continuous experiment, EtOH and H2O extracts of the fruit of Hovenia dulcis Thunb showed alcohol decomposition activity on the in vivo test using rat. These results suggest that the fruit of Hovenia dulcis Thunb may be useful in the prevention of hangover.
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